Topic: Molecular mechanisms of hematopoietic stem cell aging

Zhenyu Ju

    Dr. Zhenyu Ju has been focusing on molecular mechanisms of stem cell aging and related diseases using animal models. His research achievements include: Elucidating the endogenous molecular mechanisms of telomere shortening in stem cell senescence; Stem cell function and homeostasis affected by telomere shortening via increased inflammatory cytokines in blood circulation; The interaction between telomere damage and abnormal energy metabolism; The important role of the longevity gene Sirt6 in the homeostasis of hematopoietic stem cells.

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