Dr. Zhenyu Ju has been focusing on molecular mechanisms of stem cell aging and related diseases using animal models. His research achievements include: Elucidating the endogenous molecular mechanisms of telomere shortening in stem cell senescence; Stem cell function and homeostasis affected by telomere shortening via increased inflammatory cytokines in blood circulation; The interaction between telomere damage and abnormal energy metabolism; The important role of the longevity gene Sirt6 in the homeostasis of hematopoietic stem cells.