Dr. Jan Karlseder obtained his PhD from the University of Vienna, Austria, where he studied the cell cycle regulation of transcription. He was a postdoctoral fellow at the Rockefeller University, NY, where he investigated mechanisms of telomere length regulation and protection. In 2002 he established his laboratory at the Salk Institute for Biological Studies in La Jolla, California, where he studies the links between DNA damage signaling and repair, telomere dynamics and cancer formation. He was promoted to the Donald and Darlene Shiley Chair Professor in 2011 and is currently the Director of the Glenn Center for Research on Aging and Co-Director of the Salk Institute’s Cancer Center. The Karlseder laboratory is using telomere shortening as model for replicative aging and is investigating how telomeric signals synergize with other cellular pathways to prevent age-associated cancer initiation.